Jonathan Chan

Clinician Investigator, MD, FRCPC

 

Appointments

  • Clinical assistant professor at the University of British Columbia
  • Rheumatologist at Artus Health Centre in Vancouver

 

Research Interests

  • Axial spondyloarthritis (ankylosing spondylitis)
  • Psoriatic arthritis

 

Dr. Chan is an assistant clinical professor at the University of British Columbia who received his bachelor of medicine and completed his medical school training at the University of Alberta in 2009.

Learn more

He studied Internal Medicine at the University of British Columbia and completed his Royal College fellowship in Rheumatology. He was awarded the 2015 Assessment of Spondyloarthritis Society (ASAS) fellowship grant and completed a clinical fellowship at the University of Toronto in axial spondyloarthritis (ankylosing spondylitis). He actively pursues research in this field and has been invited to present on this topic internationally.

 

Dr. Chan is involved in the Canadian Rheumatology Association’s therapeutics committee and was coauthor of the Canadian Spondylitis Treatment Guidelines and is the core site leader of the national spondylitis and psoriatic arthritis research cohorts (SPARCC and iPART). Additionally, he is a member of the Canadian, American and international research networks (SPARCC, GRAPPA, SPARTAN and ASAS).

Publications

 

REFEREED PUBLICATIONS

  1. Journals
  • Rohekar S, Chan J, Tse SM, Haroon N, Chandran V, Bessette L, et al. A Brief Review of the 2014 Update on the Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Treatment Recommendations for the Management of Spondyloarthritis Part 1: Principles of the Management of Spondyloarthritis in Canada. J Rheumatol. 2015 Apr;42(4):654-64.

 

  • Rohekar S, Chan J, Tse SM, Haroon N, Chandran V, Bessette L, et al. A Brief Review of the 2014 Update on the Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Treatment Recommendations for the Management of Spondyloarthritis Part 2: Specific Management Recommendations. J Rheumatol. 2015 Apr;42(4):665-81.

 

  • Chan J, Sari I, Haroon N. Sacroiliitis-like Changes in Two Patients with Spina Bifida. J Rheumatol. 2016 Mar; 43(3):673.

 

  • Chan J, Sari I, Salonen D, Inman RD, Haroon N. Development of a screening tool for the identification of sacroiliitis in CT scans of the abdomen. J Rheumatol. 2016; 43:9

 

  • Chan J, Sari I, Salonen D, Silverberg MS, Haroon N, Inman RD. Prevalence of sacroiliitis in inflammatory bowel disease using a standardized CT scoring system. Arthritis Care Res. 2017; July 21

 

  • Chan J, Gladman D. Oral treatment options for AS and PsA: DMARDs and small molecule inhibitors. Best Practice & Research Clinical Rheumatology. Approved and pending publication

 

  • Kelly OB, Li, N, Smith M, Chan J, Inman RF, Silverberg MS. The Prevalence and Clinical Associations of Subclinical Sacroiliitis in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018; Nov 14

 

  • Avina-Zubieta J, Chan J, De Vera M, Sayre E, Choi HK, Esdaile JM. The risk of venous thromboembolism in ankylosing spondylitis: a general population-based study. Annals of the Rheumatic Diseases 2019; 78:480-485

 

  • Huang S, Chan J, Bruyere H, Allan LL, Gerrie AS, Toze CL. Chronic lymphocytic leukemia patients with HLA-B27 referred for allogenic hematopoietic stem cell transplantation do not have worse outcomes: results of a population-based series analysis in British Columbia, Canada. Leukemia Research. 2019 Jul;84:106193

 

SUBMITTED WORK

  • Sari I, Chan J, Johnson SR, Inman RD, Haroon N. Progression to Radiographic Sacroiliitis in Patients with Non-diagnostic Sacroiliac Joints: Results from a Longitudinal Observational Cohort of AxSpA Patients

 

NON-REFEREED PUBLICATIONS

  • Chan J, Kur J. Update on Rheumatologist demographics in British Columbia. CRAJ 2014 Vol 24, Number 4:15.

 

ABSTRACTS

  • What Is the Impact of Imaging on Diagnostic Ascertainment of Patients Presenting with Undiagnosed Back Pain in Routine Practice and the Impact of Central Reading? Data from the Screening in Axial Spondyloarthritis in Psoriasis, Iritis, and Colitis Cohort. Oral presentation at ACR Chicago 2018.

 

  • Construct Validation of the Screening for Inflammatory Pain in the Lower Back Questionnaire: Data from the Screening in Axial Spondyloarthritis in Psoriasis, Iritis, and Colitis Cohort. Poster presentation at ACR Chicago 2018.

 

  • Arendse R, Jaroszynska A, Haaland D, Boulos P, Fortin I, Kherani R, Masetto A, Chan J, Psaradellis E, Stutz M, Osborne B, Nantel F, Lehman AJ. Safety and Effectiveness of Ustekinumab for the Treatment of Psoriatic Arthritis over a 6 Month Period. Poster presentation at ACR San Diego 2017 and CRA Vancouver 2018.

 

  • Maksymowych WP, Carmona R, Yeung J, Chan J et al. Diagnostic Ascertainment of Axial Spondyloarthritis in Patients Presenting with Undiagnosed Back Pain: What is the Impact of MRI in Rheumatological Practice? Poster presentation at ACR San Diego 2017 and CRA Vancouver 2018. International congress on Spondyloarthritis at Gent 2018

 

  • Carmona R, Yeung J, Chan J et al. Which Criteria for Inflammatory Back Pain in Spondyloarthritis are Optimal? Data from Unselected Patients with Undiagnosed Back Pain in the Screening for Axial Spondyloarthritis Study. Poster presentation at ACR San Diego 2017, EULAR Madrid 2017, and CRA Vancouver 2018.

 

  • Maksymowych WP, Carmona R, Yeung J, Chan J et al. Central Reader Assessment of Imaging in Axial Spondyloarthritis: What is the Potential Impact on the Performance of the ASAS Classification Criteria? Poster presentation at CRA Vancouver 2018.

 

  • Chan J, So ACL, Sayre EC, Avina-Zubieta JA. Risk of venous thromboembolism in ankylosing spondylitis: a general population-based study. Podium presentation at ACR San Diego 2017.

 

  • So ACL, Chan J, Sayre EC, Avina-Zubieta JA. Risk of myocardial infarction and cerebrovascular accident in ankylosing spondylitis: a general population-based study. Podium presentation at ACR San Diego 2017.

 

  • Carmona R, Yeung J, Masetto A, Martin L, Keeling S, Chan J, Mosher D, Ziouzina O, Paschke J, Carapellucci A, Lambert R, Maksymowych WP. Which criteria for inflammatory back pain in spondyloarthritis are optimal? Data from the screening for axial spondyloarthritis in psoriasis, iritis, and colitis study (SASPIC). Poster at CRA Ottawa 2017.

 

  • Sari I, Omar A, Chan J, Bedaiwi M, Ayearst R, Haroon N, Inman RD. What is the clinical utility of MR Imaging in the Management of Nr-Axspa Patients? Poster presentation at the American College of Rheumatology Meeting San Francisco, USA Nov 2015.

 

  • Sari I, Chan J, Omar A, Bedaiwi M, Ayearst R, Inman RD, Haroon N. Factors Predictive of Radiographic Progression in Ankylosing Spondylitis. Poster presentation at the American College of Rheumatology Meeting San Francisco, USA Nov 2015.

 

  • Omar A, Sari I, Chan J, Haroon N, Inman RD. Twitter and Rheumatology: Significant and Incremental Growth in Usage. Poster presentation at the American College of Rheumatology Meeting San Francisco, USA Nov 2015.

 

  • Sari I, Chan J, Omar A, Bedaiwi M, Haroon N, Inman RD. Clinical Characteristics of Axial Spondyloarthritis Patients Progressing from Non-Diagnostic to Diagnostic Radiographic Sacroiliitis. Poster presentation at the American College of Rheumatology Meeting San Francisco, USA Nov 2015.

 

  • Chan J, Sari I, Salonen D, Inman RD, Haroon N. Development of a Novel SI Joint CT score for the diagnosis of Axial Spondyloarthritis. Poster presentation at the American College of Rheumatology Meeting San Francisco, USA Nov 2015.

 

  • Chan J, Sari I, Salonen D, Silverberg M, Haroon N, Inman RD. Prevalence of Sacroliitis in Inflammatory Bowel Disease Using a Standardized CT Scoring System. Guided poster tour at the American College of Rheumatology Meeting San Francisco, USA Nov 2015.

 

  • Chan J, Sari I, Salonen D, Silverberg M, Inman RD, Haroon N. Abdominal X-rays can Reliably Detect the Majority of CT Positive Sacroiliitis in an IBD Cohort. Poster presentation at the American College of Rheumatology Meeting San Francisco, USA Nov 2015.

 

  • Chan J, Sari I, Salonen D, Inman RD, Haroon N. Development of a Novel SI Joint CT score for the diagnosis of Axial Spondyloarthritis. Guided poster tour presented at the European League Against Rheumatism Meeting Rome, Italy June 2015.

 

  • Chan J, Sari I, Salonen D, Inman RD, Haroon N. Development of a Novel SI Joint CT score for the diagnosis of Axial Spondyloarthritis. Podium presentation presented at the Ogryzlo Day Department of Rheumatology Research Day, University of Toronto June 2015.

 

  • Chan J, Sari I, Salonen D, Silverberg M, Haroon N, Inman RD. Prevalence of Sacroliitis in Inflammatory Bowel Disease Using a Standardized CT Scoring System. Guided poster tour presented at the Ogryzlo Day Department of Rheumatology Research Day, University of Toronto June 2015.

 

  • Chan J, Sari I, Salonen D, Silverberg M, Inman RD, Haroon N. Abdominal X-rays can Reliably Detect the Majority of CT Positive Sacroiliitis in an IBD Cohort. Guided poster tour presented at the Ogryzlo Day Department of Rheumatology Research Day, University of Toronto June 2015.

 

  • Chan J, Sari I, Salonen D, Inman RD, Haroon N. Development of a Novel SI Joint CT score for the diagnosis of Axial Spondyloarthritis. Guided poster tour presented at the Ontario Rheumatology Association Annual meeting May 2015.

 

  • Sari I, Chan J, Omar A, Bedawi M, Ayearst R, Inman RD, Haroon N. Clinical factors at baseline predictive of subsequent radiographic progression in ankylosing spondylitis. Guided poster tour presented at the Ogryzlo Day Department of Rheumatology Research Day, University of Toronto June 2015.

 

  • Sari I, Omar A, Chan J, Bedawi M, Ayearst R, Haroon N, Inman RD. What is the clinical utility of MR imaging in the management of nr-axSpA patients? Guided poster tour presented at the Ogryzlo Day Department of Rheumatology Research Day, University of Toronto June 2015.

 

BOOKS

  1. Authored
  2. Edited
  3. Chapters
  • Chan J, Haroon N. NSAID Therapy in Axial Spondyloarthritis. In Axial Spondyloarthritis. Inman RD, Sieper J (ed). Oxford University Press.

 

OTHER WORK

  • International Psoriasis and Arthritis Research Team (iPART): Susceptibility Factors for Arthritis in Subjects with Psoriasis

a. The purpose of the study is to identify differences between genetic makeup of psoriasis patients with and without  arthritis as well as to develop a web-based database of psoriasis patients for future genetic studies. My role is to assess patients with psoriasis for extent of skin and joint disease using the iPART physician protocol. DNA samples are taken from each patient and assessments are made on an annual basis.

b. Local principal investigators: Dr. Jan Dutz and Dr. Jonathan Chan