Deborah A. Marshall

Senior Scientist, Health Services Research and Health Economics, PhD



  • Professor, Department of Community Health Sciences, Cumming School of Medicine, University of Calgary

Research Interests

  • Health Economics
  • Osteoarthritis

Deborah A. Marshall is the Arthur J.E. Child Chair of Rheumatology Outcomes Research and former Canada Research Chair, Health Services and Systems Research (2008-2018). In addition, she is a member of the O’Brien Institute of Public Health and the McCaig Institute of Bone and Joint Health and a Senior Scientist at Arthritis Research Canada.

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Dr. Marshall has experience in technology assessment agencies, academia and pharmaceutical and diagnostics industry research settings in Canada, the United States, and Europe. Dr Marshall focuses her research program on methods to improve the effectiveness and efficiency of health care services in the context of precision medicine and patient-centeredness. Her research assesses the value of health care interventions through measurement of patient preferences, cost-effectiveness analysis, and simulation modeling of health care.

She was the Project Lead for a US National Institutes of Health Program Grant on Translational and Policy Research in Personalized Medicine, which develops evidence to assess how precision medicine can improve health outcomes. She is a founding co-investigator of the innovative Patient and Community Engagement Research (PaCER) Program at the University of Calgary which trains patients to design and conduct health research, using specific adapted methods of qualitative inquiry. Dr. Marshall is the co-lead of the Economics platform for UCAN CANDU – Canada-Netherlands Personalized Medicine Network in Childhood Arthritis and Rheumatic Disease funded by the CIHR Personalized Medicine in Inflammation Network. Dr. Marshall is also the co-lead of the Patient Engagement theme for IMAGINE (Inflammation, Microbiome, and Alimentation: Gastro-Intestinal and Neuropsychiatric Effects) – a CIHR Strategy for Patient Oriented Research (SPOR) Chronic Disease Network.

Dr. Marshall is an active member of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) as the Past President of the Board of Directors, the Chair of the Dynamic Simulation Modeling Applications in Health Care Delivery Research Task Force and as a member of the Patient Preferences Special Interest Group, the Optimization Methods Task Force and co-author of related ISPOR Task Force Reports. She has also served as a member of the Board of Directors for Health Technology Assessment International (HTAi). She is currently the co-chair of the Scientific Research Committee and Board of Directors of the Arthritis Alliance of Canada (AAC), and a member of the Scientific Advisory Committee of the Alberta PROMs & EQ-5D Research & Support Unit (APERSU).


Durand C, Maysoon E, Marshall DA, Bansback N, Hazlewood G. Patient preferences for disease modifying anti-rheumatic drug treatment in rheumatoid arthritis: A systematic review. Journal of Rheumatology April 2019. In press (Doi: 10.3899/jrheum.181165)


Jin X, Al Sayah F, Ohinmaa A, Marshall DA, Smith C, Johnson JA. The EQ-5D-5L Is Superior to the -3L Version in Measuring Health-related Quality of Life in Patients Awaiting Hip or Knee Arthroplasty. Clinical Orthopedics and Related Research. In press. Feb 2019 (Doi: 10,1097/CORR.0000000000000662)


Lopatina E, Miller J, Teare S, Marlett N, Patel J, Barber CE, Mosher D, Wasylak T, Woodhouse L, Marshall DA. The voice of patients in system redesign: A case study of redesigning a centralized system for intake of referrals from primary care to rheumatologists for patients with suspected rheumatoid arthritis. Health Expectations, December 2018. https://doi.org/10.1111/hex.12855


Carr E., Patel J, Ortiz M, Miller J, Teare S, Barber CEH, Marshall DA. Co-design of a patient experience survey for arthritis central uptake: an example of meaningful patient engagement in healthcare design. BMC Health Services Research, June 2019;19:355


Barber CE, Sandhu N, Rankin J, MacMullan P, Marshall DA, Barnabe C, Hazlewood G, Emrick A, Stevenson M, Then K, Benseler S, Twilt M, Mosher D. Rheum4U: Development and testing of a web-based tool for improving the quality of care for patients with rheumatoid arthritis. Clinical and Experimental Rheumatology Online, May 2019;37(3):0385-0392


Barber CE, Sandhu N, Rankin J, MacMullan P, Marshall DA, Barnabe C, Hazlewood G, Emrick A, Stevenson M, Then K, Benseler S, Twilt M, Mosher D. Rheum4U: Development and testing of a web-based tool for improving the quality of care for patients with rheumatoid arthritis. Clinical and Experimental Rheumatology, 2018. In Press


Lopatina E, Miller J, Teare S, Marlett N, Patel J, Barber CE, Mosher D, Wasylak T, Woodhouse L, Marshall DA. The voice of patients in system redesign: A case study of redesigning a centralized system for intake of referrals from primary care to rheumatologists for patients with suspected rheumatoid arthritis. Health Expectations, December 2018. In Press https://doi.org/10.1111/hex.12855


Marshall DA, Benchimol EI, MacKenzie A, Rodriguez Duque D, MacDonald KV, Hartley T, Howley T, Hamilton A, Gillespie M, Malam F, Boycott KM. Direct healthcare costs for children diagnosed with genetic diseases are significantly higher than for children with other chronic diseases. Genetics in Medicine 2019;21(5):1049-1057.


Barber T, Sharif B, Teare S, Miller J, Shewchuk B, Green L, Marlett N, Cibere J, Mrklas K, Wasylak T, Li L, CampbellScherer D, Marshall DA. Qualitative Study to elicit patients’ and primary care physicians’ perspectives on the use of a self-management mobile health application for knee osteoarthritis. BMJ Open, 2019; 9:1-16.


Marshall DA, Liu X, Shahid R, Bertazzon S, Seidel J, Patel AB, Masr M, Barber CEH, McDonald T, Sharma R, Briggs T, Faris P, Waters N. Geographic variation in osteoarthritis prevalence in Alberta: a spatial analysis approach. Applied Geography; 103(2019):112-121. 


Barber CE, Nasr M, Barnabe C, Badley E, Lacaille D, Pope J, Cividino A, Yacyshyn E, Baillier C, Mosher D, Thomson J, Charnock C, Throne JC, Zummer M, Brophy J, Ruban T, Ahulwalia V, McDougall R, Marshall DA. Planning for the rheumatologist workforce: Factors associated with work hours and volumes. Journal of Clinical Rheumatology 2019;25(3):142-146


Greenwood-Lee J, Jewett L, Woodhouse L, Marshall DA. A categorisation of problems and solutions to improve patient referrals from primary to specialty care. BMC Health Services Research. 2018; 18(1):986. 


Collins K, Sharif B, Sanmartin C, Herzog W, Chin R, Marshall DA. Association of metabolic markers with selfreported osteoarthritis among middle-aged BMI-defined non-obese individuals: a cross-sectional study. BMC Obesity 2018;5(23). 


Crown W, Buyukkaramikli N, Sir M, Thokala P, Morton A, Marshall DA, Tosh J, Ijzerman M, Padula W, Pasupathy K. Application of Constrained Optimization Methods in Health Services Research: Report 2 of the ISPOR Optimization Methods Good Practices Task Force. Value in Health, September 2018; 21(9):1019-1028


Regier DA, Weymann D, Buchanan J, Marshall DA, Wordsworth S. Valuation of health and non-health benefits from next generation sequencing: approaches, challenges, and solutions. Value in Health, September 2018; 21(9):10431047.


Wordswoth S, Doble B, Payne K, Buchanan J, Marshall DA, McCabe C, Regier DA. Using ‘big’ data in the costeffectiveness analysis of genomic-based diagnostic tests: challenges and potential solutions. Value in Health, September 2018; 21(9):1048-1053


Phillips KA, Deverka PA, Marshall DA, Wordsworth S, Regier DA, Christensen KD, Buchanan J. Methodological issues in assessing the economic value of next-generation sequencing tests: many challenges and not enough solutions. Value in Health, September 2018; 21(9): 1033-1042


Conner-Spady B, Marshall DA, Bohm E, Dunbar MJ, Noseworthy TW. Comparing the validity and responsiveness of the EQ-5D-5L to the Oxford hip and knee scores and SF-12 in osteoarthritis patients 1 year following total joint replacement. Quality of Life Research, May 2018; 27(5):1311-1322


Marshall DA, Deal K, Conner-Spady B, Bohm E, Hawker G, Loucks L, MacDonald KV, Noseworthy T. How do patients trade-off surgeon choice and waiting times for total joint replacement: A discrete choice experiment. Osteoarthritis and Cartilage, 2018; 26:522-530


Westby MD, Marshall DA, Jones A. Development of quality indicators for hip and knee arthroplasty rehabilitation. Osteoarthritis and Cartilage. 2018; 26(1):370-382


Damani Z, MacKean G, Bohm E, Noseworthy T, Wang J, DeMone B, Wright B, Marshall DA. Insights from the design and implementation of a single-entry model of referral for total joint replacement surgery: Critical success factors and unanticipated consequences. Health Policy, 2018; 122(1):165-174


Barber CE, Schieir O, Lacaille D, Marshall DA, Barnabe C, Hazlewood G, Nadeau L, Thorne JC, Ahluwalia V, Bartlett SJ, Boire G, Haraoui B, Hitchon C, Keystone E, Tin D, Pope JE, Denning L, Bykerk VP, and Canadian Early Arthritis Cohort (CATCH) Investigators. High adherence observed to system-level performance measures for rheumatoid arthritis in a national early arthritis cohort over eight years. Arthritis Care & Research, 2018; 70(6):842-850.


Barber CEH, Mosher DP, Ahluwalia V, Zummer M, Marshall DA, Choquette D, Lacaille D, Bombardier C, Lyddiatt A, Chandran V, Khodyakov D, Dao E, Barnabe C (for the RACCD Workshop Group). Development of a Canadian core clinical dataset to support high-quality care for Canadian patients with rheumatoid arthritis. Journal of Rheumatology, 2017; 44:1813-1822.


Hazlewood G, Marshall DA, Tomlinson G, Bombardier C. A Bayesian model that jointly considers comparative effectiveness research and patients’ preferences may help inform GRADE recommendations: An application to rheumatoid arthritis treatment recommendations. J Clin Epidemiology Jan 2018;93(1):56-65


Lacny S, Wilson T, Clement F, Roberts D, Faris P, Ghali W, Marshall DA. Kaplan-Meier survival analysis overestimates cumulative incidence of health-related events in competing risk settings: A meta-analysis. J Clin Epi 2018, 93(1):23-35


Shklarov S, Marshall DA, Wasylak T, Marlett NJ. “Part of the Team”: Mapping the outcomes of training patients for new roles in health research and planning. Health Expectations, 2017;20:1428-1436 


Jansen E, Marshall DA, Hauber BA, Bridges JFP. Improving the quality of discrete-choice experiments in health: How can we assess validity and reliability? Expert Review of Pharmacoeconomics & Outcomes Research, Oct 2017; 17(6):531-542.


Lopatina E, Damani Z, Bohm E, Noseworthy T, Conner-Spady B, MacKean G, Simpson C, Marshall DA. Single-Entry Models (SEMs) for Scheduled Services: Towards a Roadmap for the Implementation of Recommended Practices. Health Policy, Sept 2017;121(9):963-970.


Whitty JA, Fraenkel L, Saigal CS, Groothuis-Oudshoorn CGM, Regier DA, Marshall DA. Assessment of Individual Patient Preferences to Inform Clinical Practice. Patient. 2017 Jun 8. doi: 10.1007/s40271-017-0254-8. [Epub ahead of print] PubMed PMID: 28597378. https://www.ncbi.nlm.nih.gov/pubmed/28597378


Shklarov S, Marshall DA, Wasylak T, Marlett NJ. “Part of the Team”: Mapping the outcomes of training patients for new roles in health research and planning. Health Expectations, 2017; doi: 10.1111/hex.12591. https://doi.org/10.1111/hex.12591


Carr EC, Babione JN, Marshall DA. Translating research into practice through user-centered design: An application for osteoarthritis healthcare planning. Int J Med Inform. 2017 Aug;104:31-37. doi: 10.1016/j.ijmedinf.2017.05.007. Epub 2017 May 13. PubMed PMID: 28599814. https://www.ncbi.nlm.nih.gov/pubmed/28599814


Lopatina E, Donald F, DiCenso A, Martin-Misener R, Kilpatrick K, Bryant-Lukosius D, Carter N, Reid K, Marshall DA. Economic evaluation of nurse practitioner and clinical nurse specialist roles: A methodological review. Int J Nurs Stud. 2017 Jul;72:71-82. doi: 10.1016/j.ijnurstu.2017.04.012. Epub 2017 May 4. PubMed PMID: 28500955. https://www.ncbi.nlm.nih.gov/pubmed/28500955


Garner S, Lopatina E, Rankin JA, Marshall DA. Nurse-led Care for Patients with Rheumatoid Arthritis: A Systematic Review of the Effect on Quality of Care. J Rheumatol. 2017 Jun;44(6):757-765. doi: 10.3899/jrheum.160535. Epub 2017 Feb 15. PubMed PMID: 28202747. https://www.ncbi.nlm.nih.gov/pubmed/28202747


Marshall DA, MacDonald KV, Robinson JO, Barcellos LF, Gianfrancescio M, Helm M, McGuire A, Green RC, Douglas MP, Goldman MA, Phillips KA. The price of whole genome sequencing may be decreasing, but who will be sequenced? Personalized Medicine May 2017;14(3):203-211. doi: 10.2217 /pme.2016.0075. https://doi.org/10.2217/pme-2016-0075


Khodyakov D, Grant S, Barber CE, Marshall DA, Esdaile JM, Lacaille D. Acceptability of an online modified Delphi panel approach for developing health services performance measures: results from 3 panels on arthritis research. J Eval Clin Pract. 2017 Apr;23(2):354-360. doi: 10.1111/jep.12623. Epub 2016 Sep 13. PubMed PMID: 27619536. https://www.ncbi.nlm.nih.gov/pubmed/27619536


Crown W, Buyukkaramikli N, Thokala P, Morton A, Sir MY, Marshall DA, Tosh J, Padula WV, Ijzerman MJ, Wong PK, Pasupathy KS. Constrained Optimization Methods in Health Services Research-An Introduction: Report 1 of the ISPOR Optimization Methods Emerging Good Practices Task Force. Value Health. 2017 Mar;20(3):310-319. doi: 10.1016/j.jval.2017.01.013. PubMed PMID: 28292475. https://www.ncbi.nlm.nih.gov/pubmed/28292475


Collins KH, Sharif B, Sanmartin C, Reimer RA, Herzog W, Chin R, Marshall DA. Association of body mass index (BMI) and percent body fat among BMI-defined non-obese middle-aged individuals: Insights from a population-based Canadian sample. Can J Public Health. 2017 Mar 1;107(6):e520-e525. doi: 10.17269/cjph.107.5652. PubMed PMID: 28252369. https://www.ncbi.nlm.nih.gov/pubmed/28252369


Sharif B, Garner R, Hennessy D, Sanmartin C, Flanagan W, Marshall DA. Productivity costs of work loss associated with osteoarthritis in Canada from 2010 to 2031. Osteoarthritis and Cartilage, March 2017;25(2): 249-258. doi: 10.1016/joca.2016.09/011. PMID 27666512. https://www.ncbi.nlm.nih.gov/pubmed/27666512


Damani Z, Conner-Spady B, Nash T, Tom Stelfox H, Noseworthy TW, Marshall DA. What is the influence of single-entry models on access to elective surgical procedures? A systematic review. BMJ Open. 2017 Feb 24;7(2):e012225. doi: 10.1136/bmjopen-2016-012225. PubMed PMID: 28237954; PubMed Central PMCID: PMC5337661. https://www.ncbi.nlm.nih.gov/pubmed/28237954


Barber CE, Jewett L, Badley EM, Lacaille D, Cividino A, Ahluwalia V, Averns H, Baillie C, Ellsworth J, Pope J, Levy D, Charnock C, McGowan C, Thorne JC, Barnabe C, Zummer M, Lundon K, McDougall RS, Thomson JG, Yacyshyn EA, Mosher D, Brophy J, Ruban TN, Marshall DA. Stand Up and Be Counted: Measuring and Mapping the Rheumatology Workforce in Canada. J Rheumatol. 2017 Feb;44(2):248-257. doi: 10.3899/jrheum.160621. Epub 2016 Dec 1. PubMed PMID: 27909087. https://www.ncbi.nlm.nih.gov/pubmed/27909087


Phillips KA, Douglas MP, Trosman JR, Marshall DA. “What Goes Around Comes Around”: Lessons Learned from Economic Evaluations of Personalized Medicine Applied to Digital Medicine. Value Health. 2017 Jan;20(1):47-53. doi: 10.1016/j.jval.2016.08.736. PubMed PMID: 28212968; PubMed Central PMCID: PMC5319740. https://www.ncbi.nlm.nih.gov/pubmed/28212968


Marshall DA, Gonzalez JM, MacDonald KV, Johnson FR. Estimating Preferences for Complex Health Technologies: Lessons Learned and Implications for Personalized Medicine. Value Health. 2017 Jan;20(1):32-39. doi: 10.1016/j.jval.2016.08.737. PubMed PMID: 28212966; PubMed Central PMCID: PMC5319756. https://www.ncbi.nlm.nih.gov/pubmed/28212966


Marshall DA, Gonzalez JM, Johnson FR, MacDonald KV, Pugh A, Douglas MP, Phillips KA. What are people willing to pay for whole-genome sequencing information, and who decides what they receive? Genet Med. 2016 Dec;18(12):1295-1302. doi: 10.1038/gim.2016.61. Epub 2016 Jun 2. PubMed PMID: 27253734; PubMed Central PMCID: PMC5133139. https://www.ncbi.nlm.nih.gov/pubmed/27253734


Marshall DA, Lopatina E, Lacny S, Emery CA. Economic impact study: neuromuscular training reduces the burden of injuries and costs compared to standard warm-up in youth soccer. Br J Sports Med. 2016 Nov;50(22):1388-1393. doi: 10.1136/bjsports-2015-095666. Epub 2016 Mar 31. PubMed PMID: 27034127. https://www.ncbi.nlm.nih.gov/pubmed/27034127


Barber CE, Esdaile JM, Martin LO, Faris P, Barnabe C, Guo S, Lopatina E, Marshall DA. Gaps in Addressing Cardiovascular Risk in Rheumatoid Arthritis: Assessing Performance Using Cardiovascular Quality Indicators. J Rheumatol. 2016 Nov;43(11):1965-1973. Epub 2016 Aug 1. PubMed PMID: 27481908. https://www.ncbi.nlm.nih.gov/pubmed/27481908


Hazlewood GS, Bombardier C, Tomlinson G, Thorne C, Bykerk VP, Thompson A, Tin D, Marshall DA. Treatment preferences of patients with early rheumatoid arthritis: a discrete-choice experiment. Rheumatology (Oxford). 2016 Nov;55(11):1959-1968. Epub 2016 Jul 31. PubMed PMID: 27477807. https://www.ncbi.nlm.nih.gov/pubmed/27477807


Damani Z, MacKean G, Bohm E, DeMone B, Wright B, Noseworthy T, Holroyd-Leduc J, Marshall DA. The use of a policy dialogue to facilitate evidence-informed policy development for improved access to care: the case of the Winnipeg Central Intake Service (WCIS). Health Res Policy Syst. 2016 Oct 18;14(1):78. PubMed PMID: 27756401; PubMed Central PMCID: PMC5070349. https://www.ncbi.nlm.nih.gov/pubmed/27756401


Miller JL, Teare SR, Marlett N, Shklarov S, Marshall DA. Support for Living a Meaningful Life with Osteoarthritis: A Patient-to-Patient Research Study. Patient. 2016 Oct;9(5):457-64. doi: 10.1007/s40271-016-0169-9. PubMed PMID: 27085710. https://www.ncbi.nlm.nih.gov/pubmed/27085710


Klein AV, Hardy S, Lim R, Marshall DA. Regulatory Decision Making in Canada-Exploring New Frontiers in Patient Involvement. Value Health. 2016 Sep; 19(6):730-733. doi: 10.1016/j.jval.2016.03.1855. Epub 2016 May 6. PubMed PMID: 27712698. https://www.ncbi.nlm.nih.gov/pubmed/27712698


Lacny S, Zarrabi M, Martin-Misener R, Donald F, Sketris I, Murphy AL, DiCenso A, Marshall DA. Cost-effectiveness of a nurse practitioner-family physician model of care in a nursing home: controlled before and after study. J Adv Nurs. 2016 Sep;72(9):2138-52. doi: 10.1111/jan.12989. Epub 2016 Apr 27. PubMed PMID: 27119440. https://www.ncbi.nlm.nih.gov/pubmed/27119440


Hazlewood GS, Barnabe C, Tomlinson G, Marshall DA, Devoe DJ, Bombardier C. Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis: A network meta-analysis. Cochrane Database Syst Rev. 2016 Aug 29;(8):CD010227. doi: 10.1002/14651858.CD010227.pub2. Review. PubMed PMID: 27571502. https://www.ncbi.nlm.nih.gov/pubmed/27571502


Hazlewood GS, Barr SG, Lopatina E, Marshall DA, Lupton TL, Fritzler MJ, Mosher DP, Steber WA, Martin L. Improving Appropriate Access to Care With Central Referral and Triage in Rheumatology. Arthritis Care Res (Hoboken). 2016 Oct;68(10):1547-53. doi: 10.1002/acr.22845. Epub 2016 Aug 19. PubMed PMID:26815410. https://www.ncbi.nlm.nih.gov/pubmed/26815410


MacDonald KV, Bombard Y, Deal K, Trudeau M, Leighl N, Marshall DA. The influence of gene expression profiling on decisional conflict in decision making for early-stage breast cancer chemotherapy. Eur J Cancer. 2016 Jul;61:85-93. doi: 10.1016/j.ejca.2016.03.077. Epub 2016 May 4. PubMed PMID: 27155447. https://www.ncbi.nlm.nih.gov/pubmed/27155447


van Dijk JD, Groothuis-Oudshoorn CG, Marshall DA, IJzerman MJ. An Empirical Comparison of Discrete Choice Experiment and Best-Worst Scaling to Estimate Stakeholders’ Risk Tolerance for Hip Replacement Surgery. Value Health. 2016 Jun;19(4):316-22. doi: 10.1016/j.jval.2015.12.020. Epub 2016 Mar 23. PubMed PMID:27325322. https://www.ncbi.nlm.nih.gov/pubmed/27325322


Hauber AB, González JM, Groothuis-Oudshoorn CG, Prior T, Marshall DA, Cunningham C, IJzerman MJ, Bridges JF. Statistical Methods for the Analysis of Discrete Choice Experiments: A Report of the ISPOR Conjoint Analysis Good Research Practices Task Force. Value Health. 2016 Jun;19(4):300-15. doi: 10.1016/j.jval.2016.04.004. Epub 2016 May 12. PubMed PMID: 27325321. https://www.ncbi.nlm.nih.gov/pubmed/27325321


Marshall DA, Deal K, Bombard Y, Leighl N, MacDonald KV, Trudeau M. How do women trade-off benefits and risks in chemotherapy treatment decisions based on gene expression profiling for early-stage breast cancer? A discrete choice experiment. BMJ Open. 2016 Jun 2;6(6):e010981. doi: 10.1136/bmjopen-2015-010981. https://www.ncbi.nlm.nih.gov/pubmed/27256091


Brophy J, Marshall DA, Badley EM, Hanly JG, Averns H, Ellsworth J, Pope JE, Barber CE. Measuring the Rheumatology Workforce in Canada: A Literature Review. J Rheumatol. 2016 Jun;43(6):1121-9. doi: 10.3899/jrheum.151174. Epub 2016 Apr 1. PubMed PMID: 27036382. https://www.ncbi.nlm.nih.gov/pubmed/27036382


Greenwood-Lee J, Hawe P, Nettel-Aguirre A, Shiell A, Marshall DA. Complex intervention modelling should capture the dynamics of adaptation. BMC Med Res Methodol. 2016 May 4;16:51. doi: 10.1186/s12874-016-0149-8. PubMed PMID: 27145807; PubMed Central PMCID: PMC4855763. https://www.ncbi.nlm.nih.gov/pubmed/27145807



Sharif B, Garner R, Sanmartin C, Flanagan WM, Hennessy D, Marshall DA. Risk of work loss due to illness or disability in patients with osteoarthritis: a population-based cohort study. Rheumatology (Oxford). 2016 May;55(5):861-8. doi:  10.1093/rheumatology/kev428. Epub 2016 Jan 11. PubMed PMID: 26759430. https://www.ncbi.nlm.nih.gov/pubmed/26759430


Hazlewood GS, Barnabe C, Tomlinson G, Marshall DA, Devoe D, Bombardier C. Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying antirheumatic drugs for rheumatoid arthritis: abridged Cochrane systematic review and network meta-analysis. BMJ. 2016 Apr 21;353:i1777. doi: 10.1136/bmj.i1777. Review. PubMed PMID: 27102806; PubMed Central PMCID: PMC4849170. https://www.ncbi.nlm.nih.gov/pubmed/27102806


Lacny S, Bohm E, Hawker G, Powell J, Marshall DA. Assessing the comparability of hip arthroplasty registries in order to improve the recording and monitoring of outcome. The Bone and Joint Journal, April 2016;98-B(4):442-451. doi: 10.1302/0301-620X.98B4.36501. PMID 27037425. https://www.ncbi.nlm.nih.gov/pubmed/27037425


Barber CE, Marshall DA, Mosher DP, Akhavan P, Tucker L, Houghton K, Batthish M, Levy DM, Schmeling H, Ellsworth J, Tibollo H, Grant S, Khodyakov D, Lacaille D; Arthritis Alliance of Canada Performance Measurement Development Panel. Development of System-level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada. J Rheumatol. 2016 Mar;43(3):530-40. doi: 10.3899/jrheum.150839. Epub 2016 Jan 15. PubMed PMID: 26773106. https://www.ncbi.nlm.nih.gov/pubmed/26773106


Greenwood-Lee J, Wild G, Marshall DA. Improving accessibility through referral management: Setting targets for specialist care. Health Systems, March 2016; doi: 10.1057/hs.2015.20


Douglas MP, Ladabaum U, Pletcher MJ, Marshall DA, Phillips KA. Economic evidence on identifying clinical actionable findings with whole-genome sequencing: a scoping review. Genetics in Medicine, Feb 2016;19(2):111-6. doi: 10/1038/gim.2015.69. Epub 2015 May 21. PMID 25996638. https://www.ncbi.nlm.nih.gov/pubmed/25996638


Marshall DA, Burgos-Liz L, Pasupathy K.S., Padula W.V., IJzerman M.J., Engbers J, Crown W, Wong P.K., Higashi M.K. Wiebe S, Osgood N.D. Transforming healthcare delivery: Integrating dynamic simulation modeling and big data in health economics and outcomes research. Pharmacoeconomics Feb 2016;34(2):115-26. doi: 10.1107/s40273-015-0330-7. Epub 2015 Oct 26. https://www.ncbi.nlm.nih.gov/pubmed/26497003


Barber CE, Patel JN, Woodhouse L, Smith C, Weiss S, Homik J, LeClercq S, Mosher D, Christiansen T, Howden JS, Wasylak T, Greenwood-Lee J, Emrick A, Suter E, Kathol B, Khodyakov D, Grant S, Campbell-Scherer D, Phillips L, Hendricks J, Marshall DA. Development of key performance indicators to evaluate centralized intake for patients with osteoarthritis and rheumatoid arthritis. Arthritis Res Ther. 2015 Nov 14;17:322. doi: 10.1186/s13075-015-0843-7. Review. PubMed PMID: 26568556; PubMed Central PMCID: PMC4644283. https://www.ncbi.nlm.nih.gov/pubmed/26568556


Kilpatrick K, Reid K, Carter N, Donald F, Bryant-Lukosius D, Martin-Misener R, Kaasalainen S, Harbman P, Marshall DA, Charbonneau-Smith R, DiCenso A. A Systematic Review of the Cost-Effectiveness of Clinical Nurse Specialists and Nurse Practitioners in Inpatient Roles. Nurs Leadersh (Tor Ont). 2015 Sep;28(3):56-76. Review. PubMed PMID: 26828838. https://www.ncbi.nlm.nih.gov/pubmed/26828838