Blood proteins linked to lupus will lead to better diagnosing and understanding of the disease
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Scientific Study Title:
Mapping anti-mitochondrial antibodies in systemic lupus erythematosus
Start Date:
End Date:
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Paul Fortin
Senior Scientist, Rheumatology, MD, MPH, FRCPC

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Why do this research?

Reason For Research

Lupus or systemic lupus erythematosus (SLE) is a complex and unpredictable disease that can lead to irreversible organ damage. Patients with lupus have specific proteins in their blood that are absent in healthy people. Researchers believe that these proteins could represent a new signal for diagnosing and understanding lupus.

Our goals are to:

(1) Measure the presence of 10 different specific proteins in this group of lupus patients; (2) define which of the 10 proteins is linked with lupus.

Methodology

Execution of Research

We will study blood samples and clinical data from a large group of lupus patients followed since the time of their diagnosis at yearly intervals between years 2000 and 2018.

Who is involved?

Involvement

Scientists, a biostatistician, a patient representative, and lupus patients.

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