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78 experts were identified. There were 24 from Canada, 31 from the United States, 5 from Mexico and 18 from the United Kingdom. Out of 78, 74% relied to the questionnaire. Three-quarters of those who replied were male physicians and their average age was 51 years old. The typical doctor who replied followed at least 75 people with SLE each and had four or five of their patients become pregnant every year. Survey results found:
The results reported are consistent with studies following women with lupus who have become pregnant taking antimalarials such as hydroxychloroquine. Thus, the fact that a number of studies that have followed these women have not found any toxicity is reassuring. However, one would need a much larger number of cases to feel even reasonably certain that the benefits of hydroxychloroquine in preventing flare-ups outweighed the unknown risks. The fact that the majority of lupus experts feel the drug is safe and that they have not seen any toxicity is good news. Every year, these experts see about 200 women with lupus who are pregnant.