The EULAR European Congress of Rheumatology is the primary platform for exchange of scientific and clinical information in Europe. It seeks to provide a forum of the highest standard for scientific, educational and social exchange between professionals involved in rheumatology. It also incorporates liaising with patient organizations in order to achieve progress in the clinical care of people with rheumatic diseases.
The EULAR Congress attracts over 18,000 delegates from more than 130 countries and takes place in a major European city. This year, the EULAR Congress will take place in London, England from June 3 to 6.
Below is a list of Arthritis Research Canada’s presentations at the 2026 EULAR European Congress of Rheumatology.
Conference Day 1
Wednesday, June 3, 2026
Oral Presentations
Serum IgG4:IgG ratio in participants with and without flare: an exploratory analysis of a phase 2a study of rilzabrutinib in participants with IgG4-related disease. Oral Presentation #: OP055
Research Team: Baker M, Della Torre E, Carruthers M, Stone JH, Choi J, Mannent L, Hagino O.
This study found that people with Immunoglobulin G4-related disease (IgG4 disease) whose disease was well controlled without any flares while taking a new drug called rilzabrutinib had large decreases in harmful IgG4 protein levels, while those whose disease flared did not, with a lesser effect on other antibody production necessary for immune response to infections. This study supports the expected mechanism of action of rilzabrutinib in controlling disease activity by selectively affecting IgG4 and that assessing IgG4 blood levels can be useful to track treatment response. A larger multinational controlled trial is underway to confirm those findings.
Glucocorticoids in giant cell arteritis: changes in treatment regimens and associated toxicity in real life: a national study based on the French health insurance database. Poster #: OP0121
Research Team: Beydon M, Lacaille D, Fautrel B, Seror R, Hajage D, Tubach F
Summary: This large nationwide study in France looked at people with giant cell arteritis and how much glucocorticosteroid (i.e., prednisone) treatment they received during the first two years following their diagnosis, and what side effects occurred. The authors found that in recent years, use of high-doses for prolonged periods is less frequent, while use of steroid-sparing treatments such as methotrexate and tocilizumab increased; however, overall steroid exposure in the first two years after diagnosis still remained high. They also found that using more steroid was associated with a greater risk of serious side effects, including infections, heart problems, fractures, and death. Even lower daily doses increased risk when used for long periods of time.
Dietary interventions in psoriatic arthritis (dipsa): a randomized controlled clinical trial. Oral Presentation #: OP070
Research Team: Eder L, Shahab S, Hopkins-Gillespie S, Bumbulis L, Emandoilidis H, Compher C, Scher JU, Gladman D, Cook R, Chandran V, Ogdie A.
Summary: This randomized trial studied whether different diets improve arthritis symptoms in overweight or obese people with active psoriatic arthritis. Patients were assigned to either a Mediterranean diet, a low-calorie diet aimed at weight loss, or standard dietary advice. All groups lost a modest amount of weight and had improvements in disease activity, pain, fatigue, and joint symptoms over 24 weeks; however, no diet was clearly superior to the others. The study found that greater weight loss was linked to greater improvement in symptoms. This shows that weight reduction itself helps to reduce psoriatic arthritis activity regardless of the specific diet followed.
Glp-1 receptor agonists to facilitate weight loss and improve disease activity, pain and function in patients with rheumatic and musculoskeletal disease: real-world evidence from the rheumatology informatics system for effectiveness (rise) registry. Oral Presentation #: OP0112
Research Team: McCormick N, Zhang J, Holladay EE, Soares de Moura C, Xie F, Mehta T, Curtis JR.
This large study using data collected as part of routine clinical care looked at people with rheumatic and musculoskeletal diseases who were prescribed weight-loss medications called GLP-1 drugs – semaglutide and tirzepatide. Both medications were widely used and led to meaningful weight loss over time, with tirzepatide generally producing greater weight loss than semaglutide. People without diabetes lost more weight than people with diabetes, and weight loss leveled off after about a year. Ongoing work is evaluating the effect of these drugs on arthritis outcomes.
Poster View Presentations
Disease burden and comorbidities in patients with psoriatic arthritis and concomitant obesity – a pooled analysis of three clinical trials. Poster #: POS0460
Research Team: Mease PJ, Sheesh M, Bello Vega N, Ngantcha M, Eder L, Sewerin P, Coates LC
Summary: This study found that people with psoriatic arthritis who were overweight or had obesity had more severe joint disease, worse symptoms, and more related health conditions like diabetes and heart disease than people with a healthy weight. Overall, higher body weight was linked to greater disease burden and poorer overall health. This highlights the importance of addressing overall health alongside joint disease.
The combo study: a randomized trial of deucravacitinib-tnf inhibitor combination therapy versus tnf inhibitor monotherapy in difficult-to-control psoriatic disease. Poster #: POS0499
Research Team: Merola JF, Garfinkel V, Gottlieb AB, Scher JU, Siegel E, Perez-Chada L, Eder L, Ogdie A, Reddy SM, Ritshlin CT, Proft F, Rivoal M, Dahan S, Vritzali E, Jou YM, Mease PJ.
Summary: This describes a planned clinical trial in people with psoriatic arthritis who are only partially responding to TNF inhibitor treatment. It will test whether adding a second medication called deucravacitinib improves joint and skin disease control compared to continuing on TNF inhibitor alone. The trial will also assess safety, symptoms, quality of life, and other health measures. This future research will inform a new combination treatment approach for harder-to-treat psoriatic arthritis.
Patient partnership to enhance independent living for people with arthritis. Poster #: POS0656
Research Team: Proulx L, Gewurtz R, Sohanian M, Backman C, Banfield J, Cairns B, Flynn T, Haagard A, McKinnon A, Russon N, Toupin-April K, Wilhelm L, Amina S.
Summary: This patient-led study explored everyday challenges faced by people with arthritis and how they adapt using assistive devices and practical solutions. It brought together patients, clinicians, and designers to identify unmet needs and develop priorities for independent living. Workshops highlighted the importance of inclusive design, peer support, accessible information, and involving people with lived experience in creating solutions. Overall, this study highlighted that combining lived experience with research and community collaboration can improve accessibility, independence, and participation for people living with arthritis.
Conference Day 2
Thursday, June 4, 2026
Oral Presentations
Co-developing a Flexible Care Delivery Model for Inflammatory Arthritis in Canada (FlexCare): Results from Focus Groups with Patients and Health Care Providers. Poster #: OP0141-HPR
Research Team: Bartlett SJ, Deville-Stoetzel N, McGuire E, Raptis K, DaCosta D, Lacaille D.
Summary: The authors conducted discussion groups with adults living with arthritis and with healthcare professionals (rheumatologists, nurses, pharmacists) to explore opportunities to optimize how care is delivered for inflammatory arthritis and inform the development of FlexCAre. This new arthritis care model aims to provide more flexible care, whereby the timing and type of follow-up visits are based on remote monitoring of symptoms and patient preference, to better meet the diverse needs of individuals with inflammatory arthritis. They identified 1. challenges in providing whole person care, 2. the need for interprofessional team-based support, and 3. the importance of flexible, individualized care that is tailored to each patient, as the key opportunities and challenges to inform the development of FlexCAre.
Obexelimab, a B Cell Inhibitor, in IgG4-Related Disease: Results From the Phase 3 INDIGO Trial. Oral Presentation #: OP018
Research Team: Della Torre E, Baker M, Zhang W, Perugino C, Katz G, Tanaka Y, Khosroshahi A, Kleger A, Schleinitz N, Martinez Valle F, Schulze-Koops H, Nakayamada S, Rebours V, Okazaki K, Dong L, Carruthers M, Chen LYC, Frulloni L, Meysami A, Takahashi H, Kawano M, Liu Y, Saeki T, Ebbo M, Alexander T, Gonzalez Garcia A, Karadag O, Maslinska M, Quinn S, Poma A, Wells A, Greene TJ, Stone JH, Culver EL.
Summary: This large inernational clinical trial in IgG4-related disease found that a new immune-targeting treatment (obexelimab) significantly reduced disease flares compared with placebo over one year. Patients receiving the drug were less likely to need additional glucocoticosteroid treatment (i.e. prednisone) and were more likely to achieve remission. The treatment was generally well tolerated, with no new safety concerns.
The development and validation of a diagnostic ultrasound enthesitis score (DUET) for psoriatic arthritis. Oral Presentation #: OP0180
Research Team: Eder L, Aayaba de Toledo R, Bakewell C, Carron P, Elnady B, Hadad A, Kavanaugh A, Katz A, Kohler M, Josefina M, Afgani F, Nguyen N, Nzeusseu Toukap A, Polachek A, Rodriguez E, Rosemffet M, Singh A, Stoenoiu MS, Szentpetery A, Tinazzi I, Yinh J, Yang M, Cook R, Kaeley G, Aydin S.
Summary: This study tested a new ultrasound scoring system called DUET to help diagnose early psoriatic arthritis by measuring inflammation at sites where tendon attach to bones. The score was higher in people with psoriatic arthritis and helped distinguish them from people with psoriasis without arthritis or people with non-inflammatory musculoskeletal conditions. Overall, DUET shows promise as a diagnostic tool to support early diagnosis, but it is not accurate enough to be used on its own. This study also highlights the importance of this clinical manifestation of psoriatic arthritis.
Perimenopause is associated with increased disease activity in psoriatic arthritis. Oral Presentation #: OP0246
Research Team: Eder L, Li X, Koppikar S, Lega I, Gladman D, Chandran V, Cook R.
Summary: This study found that disease activity in psoriatic arthritis increases during perimenopause compared with before or after menopause. Women reported having more joint pain, swelling, and higher overall disease scores during this stage. Fatigue increased slightly but only explained a small part of the change. This informs us that perimenopause may be an important period requiring closer clinical monitoring and highlights the importance of considering menopausal stage when interpreting disease activity scores.
Course of Itch from Systemic Sclerosis Onset: a Scleroderma Patient-centered Intervention Network Cohort Study. Oral Presentation#: OP0144-HPR
Research Team: Golberg M, Dal Santo C, Carrier ME, Kwakkenbos L, Frech T, Hoa S, Netchiporouk E, Misery L, Lapointe-McKenzie JA, Rideout S, Sauve M, Philip A, Pope J, Yosipovitch G, Bartlett SJ, Chaigne B, Fortune C, Gietzen A, Gottesman K, Guillot G, Hummers L, Lawrie-Jones A, Malcarne V, Mayes MD, Richard M, Stempel J, Wojeck R, Mouothon L, Benedetti A, Thombs B.
Summary: This study looked at how common itchiness of the skin is over time in people with systemic sclerosis and whether it changes with age or disease duration. The researchers followed over 2,000 patients worldwide and repeatedly measured whether they had itchyness and how severe it was. Regardless of age and disease duration, they found that itchy skin was quite common, affecting about one-third of patients at any point in time, and the severity remained about the same over many years. This study highlights the importance of itchy skin as a persistent symptom throughout the course of systemic sclerosis.
Sex-specific mortality and the burden of comorbidities in rheumatoid arthritis: results from the population-based captured study. Oral Presentation #: OP034
Research Team: Gomez-Puerta JA, Tebe C, Frade-Sosa B, Sarmiento-Monroy, Corzo JP, Ruiz-Esquide V, Carbonell-Abella C, Martinez-Laguna D, Sanmarti R, Aviña-Zubieta JA.
Summary: This large population-based study of 33,000 people with rheuamtoid arthritis in Catalonia, Spain, looked at whether people with rheumatoid arthritis have higher risk of death compared with the general population using administrative health data. They found that rheumatoid arthritis is associated with a modest increase in mortality compared to the general population, and that male sex and risk of other chronic diseases are the main factors influencing mortality, outweighing the direct effect of arthritis itself. This highlights the importance of sex-sensitive, integrated care that addresses risk and management of other chronic diseases linked to inflammation.
12-Lipoxygenase regulates inflammatory cell recruitment in lupus nephritis. Oral Presentation #: OP0153
Research Team: Monteil M, Allaeys I, Lévesque T, Greffard K, Tsukayama I, Bilodeau JF, Fortin P, Boilard E.
Summary: This study looked at why kidney disease develops in some people who have lupus. It found that a natural pathway that produces certain fat-based signaling molecules (called 12-lipoxygenase) helps protect the kidneys by limiting inflammation and the buildup of immune cells and platelets. When this pathway is reduced, kidney inflammation becomes worse, suggesting this pathway plays a protective role in lupus-related kidney disease and may be a potential target for future.
Patient- Reported Prevalence and Functional Impact of Digestive and Bowel Symptoms in Sjogrens Disease: Findings from a Global Survey. Poster #: OP0251-PARE
Research Team: Wang E, Schafer S, Montoya C.
Summary: Sjögren’s disease is a systemic autoimmune condition causing dryness of the mouth, yet gastrointestinal symptoms and dietary impacts are not routinely captured in standard disease activity measures. In this patient-led cross-sectional survey, digestive symptoms were very common and frequently associated with bowel disturbances, food avoidance, and reduced enjoyment of eating. These findings highlight the under-recognized burden of gastrointestinal symptoms in Sjögren’s, supporting the need for greater clinical recognition and more comprehensive, multidisciplinary management.
Poster View Presentations
Validation of the health assessment questionnaire disability index in immune checkpoint inhibitor-induced inflammatory arthritis. Poster #: POS0780
Research Team: Chubbs K, Ye C, Jamal S, Hudson M, Pope J, Appleton CT, Hoa S, Saltman A, Himel M, Maltez N, Fifi-Mah A, Ladouceur A, Colmegna I, Choi MY, Khokhar F, Elsay M, Roberts J.
Summary: This study looked at a questionnaire called the Health Assessment Questionnaire Disability Index (HAQ-DI), which measures how arthritis affects daily activities, in patients who developed inflammatory arthritis after cancer immunotherapy. The researchers found that the questionnaire was reliable, reflected disease severity, and was able to detect improvement over time in this patient population. The study shows that the HAQ-DI is a useful tool for monitoring symptoms and quality of life in patients with immune checkpoint inhibitor-induced inflammatory arthritis.
Prevalence and incidence of spondyloarthritis in Catalonia, Spain: findings from the population-based captured study.
Poster #: POS0187
Research Team: Gomez-Puerta JA, Ramírez J, Benavent D,. López-Medina C, Tebe C, Ponce A, Azuaga A, Zacarias Crovato A, Cuervo A, Farietta Varela S, Sanmarti R, Cañete Crespillo JDD, Aviña-Zubieta JA.
Summary: This population study from Catalonia, Spain looked at how common spondyloarthritis is and how often new cases occur. Researchers found that the number of people living with spondyloarthritis has increased over time, while the number of new cases each year stayed stable. They found spondyloarthritis was more common in men than women and was seen most often in young and middle-aged adults. These findings provide important real-world information to improve awareness and plan health services for this disease.
Patient preferences for hydroxychloroquine dosing in lupus care. Poster #: POS0718
Research Team: Lee GH, Kumar A, Zhang L, Choi H, Costenbader KH, Valentine K, Jorge A.
Summary: This study explored how patients with lupus balance the benefits and risks of different hydroxychloroquine doses. The researchers found that most patients were willing to accept a relatively higher risk of eye side-effects in exchange for the benefits of higher doses of hydroxychloroquine, and most preferred higher dosing even after seeing their personalized risk estimates. These results reveal that many patients prioritize lupus control over the potential risk of hydroxychloroquine side effects to the eyes, emphasizing the importance of shared decision-making about dosing.
Longitudinal serum proteomics reveals complement pathway diversity in rheumatoid arthritis. Poster #: POS0754
Research Team: Marchand B, Carrier N, Beaulieu E, Levesque D, Ramanathan B, Boisvert FM, Roux S, Marrugo J, Boire G, Allard-Chamard H.
Summary: In this study, the researchers used blood protein profiling to identify markers linked to disease activity in rheumatoid arthritis (RA). They found that people with RA had distinct patterns of serum proteins involving the complement system, and they were associated with disease activity over 12 months. This offers options for future personalized treatment approaches using medications that target complements.
Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors vs. ACE inhibitors/angiotensin II receptor blockers for primary gout prevention among patients with heart failure: target trial emulation studies Poster #: POS0842
Research Team: McCormick N, Yokose C, Rai SK, Lu L, Choi HK.
Summary: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been shown to lower serum urate levels and have been associated with lower rates of gout flares among people with type 2 diabetes, but while SGLT2i are increasingly being prescribed for other conditions, including heart failure, the generalisability of these gout benefits beyond diabetes were unknown. This study showed that, among people with heart failure, the risk of developing gout and rates of gout flares were lower among people starting SGLT2i than people starting another type of heart failure medications.
Induction of remission in people with newly-diagnosed antineutrophil cytoplasmic antibody-associated vasculitis: a simulation modeling approach. Poster #: POS0877
Research Team: Patel N, Wu A, Miloslavsky E, Reynolds G, Qian Y, Stone JH, Choi H, Unizony SI, Merkel P, Hyle E.
Summary: This study expanded and validated a simulation model of ANCA-associated vasculitis to better reflect the early phase after diagnosis, when patients undergo treatment to induce remission. The updated model incorporated risks such as remission, relapse, infection, kidney failure, diabetes, and death, and its predictions closely matched clinical trial and real-world data. Overall, the model provides a more accurate tool for understanding early ANCA-associated vasculitis outcomes.
Predictors of sustained drug-free remission in systemic lupus erythematosus (SLE). Data from the SLICC (Systemic Lupus International Collaborating Clinics) inception cohort. Poster #: POS0711
Research Team: Ugarte-Gil M, Rahman A, Kamen DL, Kalunian KC, Svenungsson E, Legge A, Hanly J, Urowitz MB, Godon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Clarke AE, Wallace DJ, Isenberg D, Merrill J, Fortin P, Gladman D, Bruce I, Petri M, Ginzler EM, Dooley MA, Ramsey-Goldman R, Manzi S, Jonsen A, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, Jacobsen S, Peschken C, Dinu Askanase A, Pons-Estel B, Alarcon GS, van Vollenhoven, RF.
Summary: This study explored how often patients with lupus achieve long-term remission without needing medications and what factors predict this outcome. The authors found that only a small group of patients achieved sustained drug-free remission. Older age at diagnosis and some demographic factors were linked to a higher chance of remission, while Black, Asian and Hispanic ethnicities, and having more severe disease, were associated with lower chances of remission. This study reveals that sustained drug-free remission in lupus is uncommon and is influenced by both patient characteristics and disease severity.
Patient-and Public-Led research: A scoping review with implications for rheumatic and musculoskeletal disease research. Poster #: POS0816-PARE
Research Team: Wang E, Truong L, Hassen N Qureshi E, Lin M, Lowthian T, Merry K, Gainforth H, Oelke N, Curran J, Li L.
Summary: This review examined how patient- and public-led research, where individuals with lived experience hold decision-making power or “Empower” on the IAP2 spectrum of patient engagement —is defined and practiced, and found that it remains inconsistently conceptualized and poorly defined. Overall, the findings demonstrate that patients and the public can assume leadership roles comparable to researchers, highlighting the need for clearer definitions to support rigorous design, implementation, and evaluation of future endeavors.
Oral Presentations
Effect of the scleroderma patient-centered intervention network self-management (spin-self) program on disease management self-efficacy: a two-arm parallel partially nested randomised controlled trial. Oral Presentation #: OP026-HPR
Research Team: Carrier ME, Kwakkenbos L, Golberg M, Nordlund J, Henry RS, M. E. Carrier1, L. Cañedo, D’Onofrio M, Burger T, Gietzen A, Konrad V, Vidricaire L, Dyas L, van Breda W, Fedoruk C, Grech T, Gholizadeh A, Hudson M, Jewett LR, Malcarne V, Mayes MD, Piotrowski P, Pope J, Sauve M, gottesman K, Bilsker D, Wurz A, Culos-Reed N, Fortune C, Guillot G, Hummers L, Lawrie-Jones A, Richard M, Welling J, Bokutron I, Mouthon L, Benedetti A, Bartlett SJ, Thombs B.
Summary: This study tested a self-management program called Scleroderma Patient-centered Intervention Network Self-Management (SPIN-SELF) Program for people with systemic sclerosis to see if it improved confidence in managing their disease. Compared with usual care, participants in the program had modest but significant improvements in self-efficacy immediately after the program and again at 3 months, along with some improvement in anxiety. The findings show the program helps people with systemic sclerosis feel more confident in managing their condition and is a useful support option.
Poster View Presentations
Preliminary evidence for the making it work program for systemic sclerosis (miw-ss) on self-efficacy compared to usual care. Poster #: POS1094-HPR
Research Team: Poole JL, Carandang K, Dionne T, Thelander M, Koch A, Lacaille D.
Summary: This study tested an adaption of the program, an online workplace support program, for people with systemic sclerosis to see if it improved confidence at work and reduced risk of job loss (work instability). Twenty four participants with systemic sclerosis were randomly assigned to the program or usual care. The program focused on coping with symptoms at work, communication, fatigue management, and job accommodations. People in the program had improvements in job-related self-efficacy, especially in communicating needs and overall confidence at work, while the control group did not. Changes in work productivity and job instability were more favorable in the intervention group, but the difference between groups was not statistically significant. Participants also valued the sense of community the program provided.
Cognitive Symptoms in SLE: Insights from the Subjective Perceived Deficit Questionnaire-20 and the Objective American College of Rheumatology Neuropsychological Battery (ACR-NB) Testing. Poster #: POS1060
Research Team: Smith J, Ederman L, Bingham K, Pozzi Kretzmann R, Tartaglia MC, Green R, Ruttan L, Choi MY, Appenmzeller S, Marzouk S, Bonilla D, Katz P, Beaton D, Gladman D, Whittall Garcia L, Touma Z, Barraclough M.
Summary: This study looked at how well patients with lupus can report their own cognitive difficulties compared with formal neuropsychological testing. Many patients reported problems with attention, memory, and planning, but these self-reported symptoms only weakly matched results from objective cognitive tests. This tells us that both patient-reported symptoms and formal testing are needed to fully understand cognitive function in lupus.
Poster Presentations
Improving adherence to fall prevention exercise in older adults with a history of falls: A cluster randomised trial of brief action planning training and digital support for physiotherapists. (Also presented at the Canadian Rheumatology Association Annual Scientific Meeting)
Poster #: POS0346-HPR
Research Team: Li LC, Xi H, Lu N, Davis J, Oakey M, Bayraktar D, Xu J, Therrien S, Seo YS, Wang E, Primeau C, Ma J, Mollins J, Shaw C, Jehu D, Liu-Ambrose T.
Summary: Falls are common and serious for older adults with arthritis, but many people stop doing fall-prevention exercises over time. This study showed that when physiotherapists received extra training in behaviour-change coaching skills and used an exercise-tracking app, older adults were more likely to keep doing their exercises, they had better physical function and they had 37% less risk of falls. Supporting physiotherapists with these skills can help older adults age more safely and independently.
Real-world persistence of first-line TNF and JAK inhibitors following csDMARD inadequate response in early RA: a prospective analysis of the Canadian Early Arthritis Cohort. Poster #: POS1327
Research Team: Schieir O, Bessette L, Bartlett SJ, Hazlewood G, Valois MF, Thorne C, Kuriya B, Allard-Chamard H, Hitchon CA, Bykerk V, Pope J.
Summary: Using data from the Canadian Early Arthritis Cohort (CATCH), this study compared how long patients with early rheumatoid arthritis stayed on two types of advanced treatments: JAK inhibitors and TNF inhibitors, after failing standard therapies (conventional synthetic DMARDs). Patients starting JAK inhibitors were more likely to stay on treatment during the first year, but over longer follow-up the difference between the two drugs disappeared, and overall long-term persistence was similar.
Flare after achieving sustained drug-free remission in SLE: higher risk in patients with high prior disease activity, and in those with renal and mucocutaneous involvement. Data from the SLICC (systemic lupus international collaborating clinics) inception cohort. Poster #: POS1354
Research Team: Ugarte-Gil M, Rahman A, Kamen DL, Kalunian KC, Svenungsson E, Legge A, Hanly J, Urowitz MB, Godon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Clarke AE, Wallace DJ, Isenberg D, Merrill J, Fortin P, Gladman D, Bruce I, Petri M, Ginzler EM, Dooley MA, Ramsey-Goldman R, Manzi S, Jonsen A, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, Jacobsen S, Peschken C, Dinu Askanase A, Pons-Estel B, Alarcon GS, van Vollenhoven, RF.
Summary: This international study followed patients with lupus who achieved sustained drug-free remission to see how often they later experienced disease flares. The authors found that even after remaining in remission off treatment for 2–5 years, a substantial proportion of patients still flared, but the risk decreased the longer remission was maintained. Flares were more likely in patients with a history of kidney or skin involvement and in those who took longer to reach remission.
Disparities in severe infection risk associated with systemic lupus erythematosus: Evidence from a causal forest analysis. Poster #: POS0030
Research Team: Zhao K, Cheer A, Xie H.
Summary: While patients with lupus generally face a higher risk of severe infections, this study uses advanced machine learning to show that this risk varies significantly between individuals. The authors identified specific high-risk subgroup such as those with prior infections or hypertension. Such subgroups may benefit from more monitoring and tailored prevention strategies.
