A study of the risk of blood clots in patients with Granulomatosis with Polyangiitis
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Scientific Study Title:
Increased Risk of Venous Thromboembolism in Patients with Granulomatosis with Polyangiitis: A Population-Based Study
Start Date:
End Date:
J. Antonio Avina-Zubieta-Website Headshot-400x400
J. Antonio Aviña-Zubieta
Senior Scientist, Rheumatology, MD, MSc, PhD, FRCP
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Neda Amiri
Clinician Investigator, BSc, MD, MHSC, FRCPC
Hyon Choi-Website Headshot-400x400
Hyon Choi
Senior Research Scientist, Rheumatology, MD, DrPH, FRCPC

Methodology

Execution of Research

Using a population-based database that includes all people living in British Columbia, we looked at the rate of venous thromboembolism (blood clots) in patients diagnosed with GPA compared to the general population (people who did not have GPA).

Findings & Next Steps

Patients with granulomatosis with polyangiitis (GPA, formerly known as Wegener’s disease) have a much higher risk of blood clots in the lungs and legs. For GPA patients, it is recommended more attention should be given to monitor for these complications, especially early after diagnosis.

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