OPTIKNEE is an international group of over 40 scientists, patients and health care professionals working on the prevention of knee osteoarthritis after injury.
In this study, we will reproduce the genetic variant detected in our patients in different types of bone cells, to develop an in vitro model for the study of atypical femur fractures. We need to understand the interaction between genetic factors and exposure to a medication like bisphosphonate.
The Canadian MSK Rehab Research Network will be designing new tools, such as online treatment programs and wearable technology (e.g., devices that measure physical activity) to create new therapy opportunities for musculoskeletal (MSK) problems like arthritis and osteoarthritis.
In Canada, about 500,000 youth hurt their knee every year while playing sports. Half of them go on to develop knee osteoarthritis (OA) at a young age. Following a knee injury, people may have weaker knee muscles, become less physically active, and gain weight. The injury, in combination with these other factors greatly raises OA risk. The treatment of youth…
Osteoarthritis (OA) is a chronic disease affecting 10-15% of Canada's population. It causes severe pain and disability, and is the leading cause of joint replacement surgery. Healthcare service planning does not currently consider patient preferences and their impact on health interventions. This could lead to the introduction of programs that patients do not use, which is a waste of system…
Studies show that most people with knee osteoarthritis (OA) aren’t diagnosed early enough, or at all. This study combines three current apps (Arthritis ID, OPEN, and FitViz) into one super-app for detecting knee OA to improve knee health.
A condition called femoroacetabular impingement (FAI) may cause hip osteoarthritis (OA), one of the most common forms of arthritis. This study will determine whether people with FAI are at a greater risk of developing OA, especially when combined with different types of physical activity.
Running is an activity that provides health benefits, but many people with knee osteoarthritis (OA) stop running because they are unsure if it is safe. This study will evaluate the effects of running on the knee joint and knee cartilage and provide answers about the safety of running after a knee OA diagnosis.
Computer simulation modeling is a technique that sees how health care interventions and policies will affect the population, before they are implemented. The STAR project aims to advance this technology and expand its use in health care policies and research, with a multi-disease computer simulation model (osteoarthritis, coronary heart disease, and diabetes) to study the health of the population.
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