Study Title: The role of physical activity in fatigue experienced by people with inflammatory arthritis: A sub-study of OPAM-IA

 

Principal Investigator:

Masoud Pourrahmat, BSc
MSc student, Department of Medicine, University of British Columbia
Trainee, Arthritis Research Canada

 

Supervisor:

Dr. Linda Li, PT, PhD
Associate Professor, Department of Physical Therapy, University of British Columbia
Senior Scientist, Arthritis Research Canada

 

Supervisory committee members:

Dr. Catherine Backman, PhD, Reg. OT(BC), FCAOT
Professor, Department of Occupational Science and Occupational Therapy, University of British Columbia

 

Dr. Lynne Feehan, BScPT, MSc, PhD
Clinical Associate Professor, Department of Physical Therapy, University of British Columbia

 

Dr. Hui Xie, BSc, MS, PhD
Professor, Faculty of Health Sciences, Simon Fraser University

 

Study Start Date: September 2017               Study End Date: TBD

 

Why do this research?

 

Fatigue is prevalent among people with inflammatory arthritis and has detrimental impact on quality of life. There is a body of evidence suggesting that increased physical activity in inflammatory arthritis leads to overall health benefits such as improving joint health, mobility, and psychological well-being.

 

Currently, the Effectiveness of Online Physical Activity Monitoring in Inflammatory Arthritis (OPAM-IA) trial is addressing the problem of inactivity in people living with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The present study will use data from the OPAM-IA trial to assess the association between physical activity and fatigue level, and determine if the physical activity counselling program being tested in OPAM-IA can reduce the fatigue experienced by the participants.

 

This study may support the future development of more effective treatment strategies for fatigue management in people living with inflammatory arthritis.

 

What will be done?

 

  1. Find the association between fatigue levels and the following: physical activity, pain, depression, sleep quality, obesity, and smoking status.

 

  1. Find the difference in the fatigue level of people receiving the OPAM-IA physical activity counselling program compared with people receiving control.

 

  1. Find out whether the change in physical activity can predict the change in fatigue.

 

Who is involved?

 

The OPAM-IA research team consists of 7 co-investigators, 6 research staff, and 12 collaborators. Approximately sixty people with RA and sixty people with SLE will be recruited. Eligibility criteria consists of:

 

  1. RA or SLE diagnosis.
  2. No previous experience in using any physical activity wearables.

 

Participants will be randomly assigned to one of the two groups to either receive the intervention immediately or wait 2 months before getting the intervention. Participants in the Immediate Group will be asked to attend a group education session, use a Fitbit Flex with the FitViz app, and receive counselling by a registered physiotherapist. Participants in the Delayed Group will wait 2 months to start the same intervention. Throughout the study, assessments will be done at the beginning, and at the end of months 2, 4, and 6. These assessments include an online questionnaire and wearing another research based accelerometer for 7 days.

 

Co-Investigators:

 

Dr. Lynne Feehan, BScPT, MSc, PhD
Clinical Associate Professor, Department of Physical Therapy, University of British Columbia

 

Dr. Antonio Aviña-Zubeita, MD, MSc, PhD
Assistant Professor, University of British Columbia

 

Dr. Charles Goldsmith, MSc, PhD
Professor, Biostatistics, Simon Fraser University

 

Dr. Anne Townsend, PhD
Research Associate, University of British Columbia

 

Dr. Catherine Backman, PhD, Reg. OT(BC), FCAOT
Professor, Department of Occupational Science and Occupational Therapy, University of British Columbia

 

Dr. Diane Gromala, PhD
Professor, Simon Fraser University

 

Dr. Chris Shaw, PhD
Associate Professor, Simon Fraser University

 

Research Staff:

 

Juliane Chien, Research Assistant, Arthritis Research Canada

Hussein Mamdani, Research Assistant, Arthritis Research Canada

Stephanie Therrien, Research Assistant, Arthritis Research Canada

Johnathan Tam, Research Coordinator, Arthritis Research Canada

Jenny Leese, PhD trainee, Arthritis Research Canada

Masoud Pourrahmat, MSc trainee, Arthritis Research Canada

 

Collaborators:

 

Greg Noonan, Mary Pack Arthritis Program

Paul Adam, Mary Pack Arthritis Program

Dr. Leigh Callahan, Thurston Arthritis Research Center

Pam Montie, Arthritis Patient Advisory Board

Cherly Koehn, Arthritis Consumer Experts

Dr. John Esdaile, University of British Columbia, Arthritis Research Canada

Dr. Kam Shojania, University of British Columbia, Arthritis Research Canada

Dr. David Collins, University of British Columbia

Dr. Jason Kur, Pacific Arthritis Centre

Dr. Jennifer Reynolds, Vancouver General Hospital

Dr. Ken Blocka, University of British Columbia

Dr. Shahin Jamal, University of British Columbia

 

Funding Agency:

 

The Arthritis Society

 

Masoud Pourrahmat is supported as a graduate student by “PRECISION: Preventing Complications from Inflammatory Skin, Joint and Bowel Conditions” a Team Grant from the Canadian Institutes of Health Research, Canada (THC-316595).

 

How do people get involved?

Please note that recruitment for this study is now closed.

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