Arthritis Research Canada at EULAR 2021
The EULAR European Congress of Rheumatology is the primary platform for exchange of scientific and clinical information in Europe. It seeks to provide a forum of the highest standard for scientific, educational and social exchange between professionals involved in rheumatology. It also incorporates liaising with patient organizations in order to achieve progress in the clinical care of people with rheumatic diseases.
The EULAR Congress attracts more than 18,000 delegates from over 130 countries and usually takes place in a major European city. Due to the ongoing COVID-19 pandemic, the EULAR Congress has moved to a virtual format this year and is taking place over four days between June 2 and 5.
Day 2: June 3, 2021
Research Spotlight
National burden of rheumatoid arthritis in Canada 1990-2017: Findings from the Global Burden of Disease Study 2017
We evaluated the impact of rheumatoid arthritis (RA) on the length and quality of life of the population of Canada. Our study showed that fewer people died prematurely, while the number of years of healthy life lost due to RA disability increased from 1990 to 2017 as a result of increasing frequency of disease. These outcomes were greatest in females and older populations, particularly over the age of 75. Canada showed more favourable outcomes when compared to other countries with similar socio-economic development levels.
Research Team: Hassen N, Lacaille D, Xu A, Sidi S, Alandejani A, Mansourian M, Sarrazadegan N, Kopec J
To learn more about Arthritis Research Canada research presented at the EULAR European Congress of Rheumatology (Day 2), please scroll down.
Extrapolation of long-term outcomes in systemic lupus erythematosus: Replicating a Hopkins Lupus Cohort analysis with the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort
As part of an effort to refine an existing disease model of short- and long-term risk outcomes that was developed in an SLE cohort at Johns Hopkins in the US, this study aims to replicate the model in an international cohort of SLE patients. The relationships between short- and long-term outcomes identified in the original analysis were broadly replicated, with differences observed likely reflecting differences in the patient populations, structure of the cohorts, and frequency of patient visits.
Research Team: Clarke AE, St-Pierre Y, Paly V, Bruce IN, Malmberg C, Briggs A, Zhang Y, Choi J, Brennan A
Factors associated with baseline hypertension in early rheumatoid arthritis: Data from a real-world large incident cohort
Approximately 1 in 4 diagnosed with rheumatoid arthritis had hypertension (HTN) reported by their rheumatologists, which is similar to that of the general population. This suggests that increased risk of HTN in rheumatoid arthritis (RA) patients may develop as RA disease or treatment time progresses. Factors that may be predictive of this excess risk will be explored in further analysis.
Research Team: Hadwen B, Stranges S, Klar N, Bindee K, Pope J, Bartlett SJ, Boire G, Bessette L, Hitchonn C, Hazlewood G, Keystone E, Schieir O, Thorne C, Tin D, Valois MF, Bykerk V, Barra L; on behalf of CATCH Investigators
Does imaging of the sacroiliac joint differ in patients presenting with undiagnosed back pain and psoriasis, acute anterior uveitis, and colitis: An inception cohort study
There has been some debate as to whether patients with psoriasis and inflammation of the spine have different findings on imaging of the spine, compared to other patients with inflammation of the spine. We did not find any differences in X-ray or MRI of the sacroiliac joints suggesting there is no major difference between these subgroups as far as imaging is concerned.
Research Team: Maksymowych WP, Weber U, Chan J, Carmona R, Yeung J, Aydin S, Reis J, Martin L, Masetto A, Ziouzina O, Mosher D, Keeling , Rohekar S, Dadashova R, Paschke J, Carapellucci A, Lambert RG
Validation of ANCA-associated vasculitis as the cause of end-stage renal disease in the United States Renal Data System
Kidney complications such as end-stage renal disease (ESRD) are common in patients with ANCA-associated vasculitis – a group of diseases characterized by inflammation and damage of small blood vessels. We examined whether diagnoses of ANCA-associated vasculitis were the primary cause of ESRD in a national registry of ESRD patients and found that there was accurate classification of ESRD due to ANCA-associated vasculitis in this database.
Research Team: Cook C, Choi H, Wallace Z
